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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GMNN All Species: 15.45
Human Site: S189 Identified Species: 34
UniProt: O75496 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.3
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75496 NP_056979.1 209 23565 S189 E D S L V E D S E I G T C A E
Chimpanzee Pan troglodytes XP_001171862 209 23550 S189 E D S L V E D S E I G T C A E
Rhesus Macaque Macaca mulatta XP_001101599 209 23555 S189 E D S V G E D S E I G T C A E
Dog Lupus familis XP_535906 427 46469 P407 E G S D V E D P D V G M C A E
Cat Felis silvestris
Mouse Mus musculus O88513 206 23281 S186 E Y S E L E D S G A G T C A E
Rat Rattus norvegicus NP_001099582 206 23103 S186 E Y S E P E D S D T G T C A E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513504 199 22131 E179 A G G D P E G E D A D T P G E
Chicken Gallus gallus NP_001026181 187 21298 E168 I E R L T G Q E S D N L E A L
Frog Xenopus laevis NP_001084216 219 25357 A194 F E D E A D M A E A R I E D E
Zebra Danio Brachydanio rerio NP_956380 241 27338 Q209 E E H E D E D Q E H D C E G E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789704 254 28148 E232 D E V F V H K E D I E D D A K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 94.7 37.7 N.A. 77.5 75.1 N.A. 56.4 49.2 48.4 41 N.A. N.A. N.A. N.A. 25.9
Protein Similarity: 100 99 97.1 41.6 N.A. 86.5 85.1 N.A. 67.9 63.1 64.3 56.8 N.A. N.A. N.A. N.A. 44.4
P-Site Identity: 100 100 86.6 60 N.A. 66.6 66.6 N.A. 20 13.3 13.3 33.3 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 93.3 73.3 N.A. 73.3 73.3 N.A. 26.6 20 33.3 40 N.A. N.A. N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 10 0 0 10 0 28 0 0 0 73 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 10 55 0 0 % C
% Asp: 10 28 10 19 10 10 64 0 37 10 19 10 10 10 0 % D
% Glu: 64 37 0 37 0 73 0 28 46 0 10 0 28 0 82 % E
% Phe: 10 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 19 10 0 10 10 10 0 10 0 55 0 0 19 0 % G
% His: 0 0 10 0 0 10 0 0 0 10 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 37 0 10 0 0 0 % I
% Lys: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 10 % K
% Leu: 0 0 0 28 10 0 0 0 0 0 0 10 0 0 10 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % N
% Pro: 0 0 0 0 19 0 0 10 0 0 0 0 10 0 0 % P
% Gln: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % Q
% Arg: 0 0 10 0 0 0 0 0 0 0 10 0 0 0 0 % R
% Ser: 0 0 55 0 0 0 0 46 10 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 10 0 0 0 0 10 0 55 0 0 0 % T
% Val: 0 0 10 10 37 0 0 0 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 19 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _